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~25 The approximate number of selenoproteins in the human proteome a small, distinguished cohort There are roughly twenty-five selenoproteins in the human proteome a small, distinguished group given the body produces tens of thousands of distinct proteins overall

In GBM, FRGs such as STEAP3, HSPB1, and MAP1LC3A affect tumor cell fate by modulating processes such as the p53 signaling pathway, senescence, and autophagy

Elife (2022) 11:e74391

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The metabolic shifts induced by GLP-1 and GIP activation create conditions where the liver preferentially mobilizes stored triglycerides

This suggests that lactylation may promote M2 macrophage polarization, thereby inducing PASMC proliferation and migration, and contributing to the development of PAH [227, 228]